Cell Biology and Genetics

Learning outcomes - - Describe the signal hypothesis - Compare and contrast co-translational and post-translational translocation - Propose a model for protein translocation based on the structures of the SecY complex - Describe the biosynthesis of integral membrane proteins

Learning Outcomes - - Distinguish between the roles of GEF, GAP and Ran in nuclear transport - Propose how structures of α and β importins inform how cargo is transported

Learning outcomes: - Understand experiments that led to the hypothesis of trafficking - Compare and contrast vesicle budding via COPI, COPII, and clathrin coats - Explain a molecular mechanism for docking and fusion of transport vesicles

Learning outcomes: - Compare and contrast cytoskeletal components - Explain how filament polarity can be identified and the role it plays in transport

- Compare and contrast different types of cell junctions - Explain how structures of integrin and cadherin inform a molecular mechanism for cell adhesion

Learning outcomes: Describe the general principles of cell signalling (amplification, ligands/receptors, G-proteins/kinases, distance, resetting, etc.), with reference to specific examples such as Nuclear Receptors, GPCRs, and RTKs

Learning outcomes covered: - Understand that the Cell Cycle is a universal feature of dividing cells from yeast to sea urchin to frog oocytes and human cells - Recall the names and order of the phases of the eukaryotic cell cycle and describe what happens in each - Describe how the Cell Cycle is regulated by CDKs and cyclins, and what happens when it becomes deregulated (i.e. cancer)

A detailed summary of all the information you'll need to complete 1st-year Genetics modules.

This compares and contrasts characteristics between bacteria, archaea, and eukaryotes in terms of cellular appearance, replication, transcription, and translation.

This describes the components in extracellular matrix and how components internal and external of the cells interact with each other to coordinate movements.