BCHE 5180/6180
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BCHE 5180/6180 Exam Final. 100% 
 
Give the general Henderson-Hasselbalch equation and sketch the plot it describes (pH against amount of NaOH added to a weak acid). On your curve label the pKa for the weak acid, and indicate the region in which the buffering capacity of the system is greatest. 
 
 
 
[ A ] 
pH pKa log [HA] 
 
The inflection point, which occurs when the weak acid has been exactly one half titrated with NaOH, occurs at a pH equal to the pKa of the weak acid. 
 
The r...
- Exam (elaborations)
- • 10 pages's •
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BCHE 5180/6180•BCHE 5180/6180
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BCHE 5180/6180 Exam Final. 100% 
 
Give the general Henderson-Hasselbalch equation and sketch the plot it describes (pH against amount of NaOH added to a weak acid). On your curve label the pKa for the weak acid, and indicate the region in which the buffering capacity of the system is greatest. 
 
 
 
[ A ] 
pH pKa log [HA] 
 
The inflection point, which occurs when the weak acid has been exactly one half titrated with NaOH, occurs at a pH equal to the pKa of the weak acid. 
 
The r...
BCHE 5180/6180: Spring Final (Graded A+) 
 
1 
3 points	Based on what you have learned about the functioning of enzymes and proteins, explain why the pH in the cell has to be buffered. 
	A large group of enzymes show a pH optimum for their activity. This value is normally close to the pH in the cell. When the pH in the cell changes this can lead to a protonation or deprotonation of an amino acid that is important for the enzymatic activity. As a result the activity will decrease. Upon large chan...
- Exam (elaborations)
- • 15 pages's •
-
BCHE 5180/6180•BCHE 5180/6180
Preview 2 out of 15 pages
BCHE 5180/6180: Spring Final (Graded A+) 
 
1 
3 points	Based on what you have learned about the functioning of enzymes and proteins, explain why the pH in the cell has to be buffered. 
	A large group of enzymes show a pH optimum for their activity. This value is normally close to the pH in the cell. When the pH in the cell changes this can lead to a protonation or deprotonation of an amino acid that is important for the enzymatic activity. As a result the activity will decrease. Upon large chan...
BCHE 5180/6180 Exam Final. 100% 
 
Give the general Henderson-Hasselbalch equation and sketch the plot it describes (pH against amount of NaOH added to a weak acid). On your curve label the pKa for the weak acid, and indicate the region in which the buffering capacity of the system is greatest. 
 
 
 
[ A ] 
pH pKa log [HA] 
 
The inflection point, which occurs when the weak acid has been exactly one half titrated with NaOH, occurs at a pH equal to the pKa of the weak acid. 
 
The r...
- Exam (elaborations)
- • 10 pages's •
-
BCHE 5180/6180•BCHE 5180/6180
Preview 2 out of 10 pages
BCHE 5180/6180 Exam Final. 100% 
 
Give the general Henderson-Hasselbalch equation and sketch the plot it describes (pH against amount of NaOH added to a weak acid). On your curve label the pKa for the weak acid, and indicate the region in which the buffering capacity of the system is greatest. 
 
 
 
[ A ] 
pH pKa log [HA] 
 
The inflection point, which occurs when the weak acid has been exactly one half titrated with NaOH, occurs at a pH equal to the pKa of the weak acid. 
 
The r...
BCHE 5180/6180 Exam Final.
- Exam (elaborations)
- • 10 pages's •
-
BCHE 5180/6180•BCHE 5180/6180
Preview 2 out of 10 pages
BCHE 5180/6180 Exam Final.
BCHE 5180/6180: Spring Final (Graded A+)
- Exam (elaborations)
- • 15 pages's •
-
BCHE 5180/6180•BCHE 5180/6180
Preview 2 out of 15 pages
BCHE 5180/6180: Spring Final (Graded A+)
BCHE 5180/6180 Exam Final 
BCHE 5180/6180 Exam Final. 100% 
 
Give the general Henderson-Hasselbalch equation and sketch the plot it describes (pH against amount of NaOH added to a weak acid). On your curve label the pKa for the weak acid, and indicate the region in which the buffering capacity of the system is greatest. 
 
 
 
[ A ] 
pH pKa log [HA] 
 
The inflection point, which occurs when the weak acid has been exactly one half titrated with NaOH, occurs at a pH equal to the pKa...
- Exam (elaborations)
- • 10 pages's •
-
BCHE 5180/6180•BCHE 5180/6180
Preview 2 out of 10 pages
BCHE 5180/6180 Exam Final 
BCHE 5180/6180 Exam Final. 100% 
 
Give the general Henderson-Hasselbalch equation and sketch the plot it describes (pH against amount of NaOH added to a weak acid). On your curve label the pKa for the weak acid, and indicate the region in which the buffering capacity of the system is greatest. 
 
 
 
[ A ] 
pH pKa log [HA] 
 
The inflection point, which occurs when the weak acid has been exactly one half titrated with NaOH, occurs at a pH equal to the pKa...
BCHE 5180/6180: Spring Final (Graded A+) 
 
BCHE 5180/6180: Spring Final (Graded A+) 
 
1 
3 points	Based on what you have learned about the functioning of enzymes and proteins, explain why the pH in the cell has to be buffered. 
	A large group of enzymes show a pH optimum for their activity. This value is normally close to the pH in the cell. When the pH in the cell changes this can lead to a protonation or deprotonation of an amino acid that is important for the enzymatic activity. As a result...
- Exam (elaborations)
- • 15 pages's •
-
BCHE 5180/6180•BCHE 5180/6180
Preview 2 out of 15 pages
BCHE 5180/6180: Spring Final (Graded A+) 
 
BCHE 5180/6180: Spring Final (Graded A+) 
 
1 
3 points	Based on what you have learned about the functioning of enzymes and proteins, explain why the pH in the cell has to be buffered. 
	A large group of enzymes show a pH optimum for their activity. This value is normally close to the pH in the cell. When the pH in the cell changes this can lead to a protonation or deprotonation of an amino acid that is important for the enzymatic activity. As a result...