Ochiengk18
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Applied Immunology
Self-tolerance and immunoregulation: mechanisms of self-tolerance, mechanisms of autoimmunity and role of genetic factor e.g. MCH in autoimmunity. Transplantation: mechanisms of graft rejection, grafting privilege sites, organ and bone marrow transplant, Immunological diseases: autoimmunity, inflammation, principles of therapy for immune-mediated diseases: anti-inflammatory agents, antagonists against proinflammatory cytokines such as TNF and IL-1, immunosuppressive drugs e.g. cyclosporine A, V...
- Class notes
- • 94 pages •
Self-tolerance and immunoregulation: mechanisms of self-tolerance, mechanisms of autoimmunity and role of genetic factor e.g. MCH in autoimmunity. Transplantation: mechanisms of graft rejection, grafting privilege sites, organ and bone marrow transplant, Immunological diseases: autoimmunity, inflammation, principles of therapy for immune-mediated diseases: anti-inflammatory agents, antagonists against proinflammatory cytokines such as TNF and IL-1, immunosuppressive drugs e.g. cyclosporine A, V...
Applied immunology
Self-tolerance and immunoregulation: mechanisms of self-tolerance, mechanisms of autoimmunity and role of genetic factor e.g. MCH in autoimmunity. Transplantation: mechanisms of graft rejection, grafting privilege sites, organ and bone marrow transplant, Immunological diseases: autoimmunity, inflammation, principles of therapy for immune-mediated diseases: anti-inflammatory agents, antagonists against proinflammatory cytokines such as TNF and IL-1, immunosuppressive drugs e.g. cyclosporine A, V...
- Class notes
- • 94 pages •
Self-tolerance and immunoregulation: mechanisms of self-tolerance, mechanisms of autoimmunity and role of genetic factor e.g. MCH in autoimmunity. Transplantation: mechanisms of graft rejection, grafting privilege sites, organ and bone marrow transplant, Immunological diseases: autoimmunity, inflammation, principles of therapy for immune-mediated diseases: anti-inflammatory agents, antagonists against proinflammatory cytokines such as TNF and IL-1, immunosuppressive drugs e.g. cyclosporine A, V...
structure of biomolecules
Occurrence of biomolecules in prokaryotic and eukaryotic cells. 
Hierarchy of biomolecule organization. Water and its properties, pH and buffers. 
Structure of amino acids & Proteins, carbohydrates, simple & complex lipids, 
nucleotides & nucleic acids 

- Book
- Class notes
- • 33 pages •
Occurrence of biomolecules in prokaryotic and eukaryotic cells. 
Hierarchy of biomolecule organization. Water and its properties, pH and buffers. 
Structure of amino acids & Proteins, carbohydrates, simple & complex lipids, 
nucleotides & nucleic acids 

Bioprocessing
Introduction to bioprocess technology. Screening, preservation and improvement of industrially important microorganisms. Upstream and downstream processing: Cell separation, cell disintegration, product purification. Scale up of protein purification: source availability; initial recovery of proteins. Removal of whole cells and cell debris. Nucleic acid removal. Concentration and primary purification. Column chromatograpy. Engineering proteins for subsequent purification. Bulk enzyme preparations...
- Class notes
- • 96 pages •
Introduction to bioprocess technology. Screening, preservation and improvement of industrially important microorganisms. Upstream and downstream processing: Cell separation, cell disintegration, product purification. Scale up of protein purification: source availability; initial recovery of proteins. Removal of whole cells and cell debris. Nucleic acid removal. Concentration and primary purification. Column chromatograpy. Engineering proteins for subsequent purification. Bulk enzyme preparations...
Drug Bioscreening
Drug bioscreening is the systematic study of substances to determine their pharmacodynamics, that is, the effects of a drug on animals and humans and on their tissues and organs; and the response to drugs by animals and humans and their tissues and organs. The substances to be tested are exposed to a process that determines those that have potential value as well as those that do not. Drug bioscreening is a scanning procedure in living organisms such as animals designed to distinguish useful fro...
- Class notes
- • 85 pages •
Drug bioscreening is the systematic study of substances to determine their pharmacodynamics, that is, the effects of a drug on animals and humans and on their tissues and organs; and the response to drugs by animals and humans and their tissues and organs. The substances to be tested are exposed to a process that determines those that have potential value as well as those that do not. Drug bioscreening is a scanning procedure in living organisms such as animals designed to distinguish useful fro...