Pacop Study guides, Class notes & Summaries

DOSAGE FORM PACOP COMPILED-PHARMACEUTICAL DOSAGE FORMS AND DRUG DELIVERY SYSTEMS (VIOLET)/DOSAGE FORM PACOP COMPILED-PHARMACEUTICAL DOSAGE FORMS AND DRUG DELIVERY SYSTEMS (VIOLET)/DOSAGE FORM PACOP COMPILED-PHARMACEUTICAL DOSAGE FORMS AND DRUG DELIVERY SYSTEMS (VIOLET)

The driving force for passive absorption of a drug is the: a. specific carrier proteins and shows saturation kinetics b. concentration gradient across a membrane separating body compartment c. both d. none - b. concentration gradient across a membrane separating body compartment Physical factors influencing absorption: a. total surface area available for absorption b. contact time at the absorption surface c. blood flow to the absorption site d. all e. none - d. all Clinical effective...

1. Pharmacodynamics is: A. The science that examines the interrelationship of the physiochemical properties of the drug and the route of administration on the rate and extent of systemic drug absorption B. The science of the kinetics of drug absorption, distribution and elimination C. The part of pharmacology, which deals with what a drug does to the body D. The science, which deals with the physiochemical properties of the drug that allow it to be designed into dosage forms E. A and B - ...

Rays which have no mass and no charge but of very high energy and excellent penetrating power are called? - Gamma Examples of antacids which cause rebound hyperacidity - NaHCO3 & CaCO3 Which anion evolves a gas with a fruity odor when treated with conc sulfuric acid and ethanol? - CH3COOWhich buffer system has been modified to include NaCl to make it isotonic with physiologic fluid? - Sorensen's Phosphate buffer Sulfide that is orange-red in color, insoluble in NH3 but soluble in exce...

2. An example of a weakly basic prodrug that when protonated, form covalent disulfide linkages with H+/K+ ATPase and inactivates it: A. Maalox® B. Nexium® C. Tagamet® D. Buscopan® - B. Nexium® 3. Anti-ulcerant drugs exert their effect through which of the following mechanism/s: I. Stimulation of protein kinases that phosphorylate H+ /K+ ATPase II. Preventing histamine from binding to its receptor in parietal cells. III. Activate inhibitory proteins that block histaming activation...

In LADMER system, L stands for liberation as the first step which determines the following aspects, except: a. onset of action c. rate of absorption b. type of preparation d. bioavailability - b. type of preparation The ultimate evaluation of dosage forms or delivery system is in: a. disintegration time c. clinical effectiveness b. thickness d. taste - c. clinical effectiveness Factor that contributes to patient's difference in drug concentration in the body, except: a. body weight c. a...

2. An example of a weakly basic prodrug that when protonated, form covalent disulfide linkages with H+/K+ ATPase and inactivates it: A. Maalox® B. Nexium® C. Tagamet® D. Buscopan® - B. Nexium® 3. Anti-ulcerant drugs exert their effect through which of the following mechanism/s: I. Stimulation of protein kinases that phosphorylate H+ /K+ ATPase II. Preventing histamine from binding to its receptor in parietal cells. III. Activate inhibitory proteins that block histaming activation...

A glucosan yield glucose units on hydrolysis. While inulin is a ____ a. fructosan b. hexosan c. pentosan d. diosan e. all of these - A The usual source of tannins from plants are from the : a. barks/stems b. seeds c. roots d. rhizomes e. all of these - A Ethanol and citric acid are produced by the cellular respiration of carbohydrates, especially a. glucose b. sucrose c. fructose d. xylose e. lactose - A Because mannitol is absorbed from the GIT and parenterally is not metabolized, then it...

1. A means of administering drugs as formulated preparations is called: a. pharmaceutical b. drug delivery system c. dosage forms d. any of the above - D 2. A manufacturer who produces the products of a company without manufacturing facilities is a/ an: a. ethical manufacturer b. proprietary manufacturer c. biological manufacturer d. toll manufacturer - D 3. Primary package system as differentiated from secondary package systems: a. are in direct contact with the product b. have a di...

In LADMER system, L stands for liberation as the first step which determines the following aspects, except: a. onset of action c. rate of absorption b. type of preparation d. bioavailability - b. type of preparation The ultimate evaluation of dosage forms or delivery system is in: a. disintegration time c. clinical effectiveness b. thickness d. taste - c. clinical effectiveness Factor that contributes to patient's difference in drug concentration in the body, except: a. body weight c. a...