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N5315 Advanced Pathophysiology

Gastrointestinal

Core Knowledge Objectives with Advanced Organizers

Gastrointestinal Bleeds

1. Analyze the etiology, clinical manifestations, and pathophysiology of the upper and lower GI

bleed and describe the implications this has for your clinical practice as a nurse practitioner.

Disease Etiology Clinical

Manifestations

Pathophysiology Implications for

Practice

Upper

GI

Bleed

Bleeding varices

(varicose veins) in

the esophagus or

stomach, peptic
...
N5315 Advanced PathophysiologyGastrointestinalCore Knowledge Objectives with Advanced Organiz/GI system- Module 9
Last document update:
ago
N5315 Advanced Pathophysiology

Gastrointestinal

Core Knowledge Objectives with Advanced Organizers

Gastrointestinal Bleeds

1. Analyze the etiology, clinical manifestations, and pathophysiology of the upper and lower GI

bleed and describe the implications this has for your clinical practice as a nurse practitioner.

Disease Etiology Clinical

Manifestations

Pathophysiology Implications for

Practice

Upper

GI

Bleed

Bleeding varices

(varicose veins) in

the esophagus or

stomach, peptic
...
N5315 Advanced Pathophysiology Hematologic System Prerequisite Knowledge Objectives with Advanced Organizers
Exam (elaborations) • 10
pages
• 2023
N5315 Advanced Pathophysiology

Hematologic System

Prerequisite Knowledge Objectives with Advanced

Organizers

Hematologic Anatomy and Physiology

1. Analyze the normal structure and function of the following
N5315 Advanced Pathophysiology Hematologic System Prerequisite Knowledge Objectives with Advanced Organizers
Last document update:
ago
N5315 Advanced Pathophysiology

Hematologic System

Prerequisite Knowledge Objectives with Advanced

Organizers

Hematologic Anatomy and Physiology

1. Analyze the normal structure and function of the following
N5315 Advanced Pathophysiology Hematologic System Prerequisite Knowledge Objectives with Advanced Organizers
Exam (elaborations) • 10
pages
• 2023
Hematologic Anatomy and Physiology

1. Analyze the normal structure and function of the following cells/organs. CH 27

Cell/Organ Structure and Function

Erythrocytes &

Iron Cycle

FIGURE 27-17

(RBC’s) most abundant cell of the body. Responsible for tissue

oxygenation. Contains: Hemoglobin, Electrolytes, [A mature

erythrocyte=no nucleus/no mitochondria, cannot synthesize protein/carry

out oxidative reactions]. Short life d//t no mitosis=100-120 days.

Biconcave disk/can be reversibly defo...
N5315 Advanced Pathophysiology Hematologic System Prerequisite Knowledge Objectives with Advanced Organizers
Last document update:
ago
Hematologic Anatomy and Physiology

1. Analyze the normal structure and function of the following cells/organs. CH 27

Cell/Organ Structure and Function

Erythrocytes &

Iron Cycle

FIGURE 27-17

(RBC’s) most abundant cell of the body. Responsible for tissue

oxygenation. Contains: Hemoglobin, Electrolytes, [A mature

erythrocyte=no nucleus/no mitochondria, cannot synthesize protein/carry

out oxidative reactions]. Short life d//t no mitosis=100-120 days.

Biconcave disk/can be reversibly defo...
N5315 Advanced Pathophysiology

Gastrointestinal

Core Knowledge Objectives with Advanced Organizers

Gastrointestinal Bleeds

1. Analyze the etiology, clinical manifestations, and pathophysiology of the upper and lower GI

bleed and describe the implications this has for your clinical practice as a nurse practitioner.

Disease Etiology Clinical

Manifestations

Pathophysiology Implications for

Practice

Upper

GI

Bleed

Bleeding varices

(varicose veins) in

the esophagus or

stomach, peptic
...
N5315 Advanced Pathophysiology Gastrointestinal Core Knowledge Objectives with Advanced Organizers Gastrointestinal Bleeds
Last document update:
ago
N5315 Advanced Pathophysiology

Gastrointestinal

Core Knowledge Objectives with Advanced Organizers

Gastrointestinal Bleeds

1. Analyze the etiology, clinical manifestations, and pathophysiology of the upper and lower GI

bleed and describe the implications this has for your clinical practice as a nurse practitioner.

Disease Etiology Clinical

Manifestations

Pathophysiology Implications for

Practice

Upper

GI

Bleed

Bleeding varices

(varicose veins) in

the esophagus or

stomach, peptic
...
N5315 Advanced Pathophysiology

Genetics

Core Knowledge Objectives with Advanced Organizers

Genetics

Chapter 4

1. Analyze the pathological processes which alter the structure and role of the DNA and

RNA molecules.

a. Describe the structure and function of the DNA molecule and its clinical

significance. PAGE 136-137

i. Four types of nitrogenous bases of DNA include adenine, cytosine,

guanine, and thymine commonly represented as their first letter. Physical

structure of DNA is the double...
N5315 Advanced PathophysiologyGeneticsCore Knowledge Objectives with Advanced Organizers
Last document update:
ago
N5315 Advanced Pathophysiology

Genetics

Core Knowledge Objectives with Advanced Organizers

Genetics

Chapter 4

1. Analyze the pathological processes which alter the structure and role of the DNA and

RNA molecules.

a. Describe the structure and function of the DNA molecule and its clinical

significance. PAGE 136-137

i. Four types of nitrogenous bases of DNA include adenine, cytosine,

guanine, and thymine commonly represented as their first letter. Physical

structure of DNA is the double...
Disorders of the Immune System

2. Differentiate between the etiology, clinical manifestations and pathophysiology of

select disorders of the immune system.

Hypersensitivity: an altered immunologic response to an antigen that results in disease

or damage to the host.

Hypersensitivity reaction: can be classified in 2 ways

- by the source of the antigen that the immune system is attacking (allergy,

autoimmunity, alloimmunity)

- by the mechanism that causes the disease (types I, II, III, IV)...
NURS 5315 Disorders of the Immune System
Last document update:
ago
Disorders of the Immune System

2. Differentiate between the etiology, clinical manifestations and pathophysiology of

select disorders of the immune system.

Hypersensitivity: an altered immunologic response to an antigen that results in disease

or damage to the host.

Hypersensitivity reaction: can be classified in 2 ways

- by the source of the antigen that the immune system is attacking (allergy,

autoimmunity, alloimmunity)

- by the mechanism that causes the disease (types I, II, III, IV)...
N5315 Advanced Pathophysiology

Inflammation and Altered Immunity

Core Knowledge Objectives with Advanced Organizers

Inflammation

1. Examine the process of inflammation.

a. Analyze the role and function of the key players in the inflammatory process and describe

the implications for clinical practice.

Key Player Role and Function

Mast Cell - Central cells of inflammation and release histamine, chemotactic factors,

cytokines, leukotrienes, prostaglandins, growth factors, and other mediato...
N5315 Advanced Pathophysiology Inflammation and Altered Immunity Core Knowledge Objectives with Advanced Organizers
Last document update:
ago
N5315 Advanced Pathophysiology

Inflammation and Altered Immunity

Core Knowledge Objectives with Advanced Organizers

Inflammation

1. Examine the process of inflammation.

a. Analyze the role and function of the key players in the inflammatory process and describe

the implications for clinical practice.

Key Player Role and Function

Mast Cell - Central cells of inflammation and release histamine, chemotactic factors,

cytokines, leukotrienes, prostaglandins, growth factors, and other mediato...
N5315 Advanced Pathophysiology

Hematologic System

Core Knowledge Objectives with Advanced Organizers

Disorders of Hemostasis

1. Examine the etiology, clinical manifestations, and the pathophysiology of disorders of

hemostasis.

a. Discuss how the
N5315 Advanced Pathophysiology Hematologic System Core Knowledge Objectives with Advanced Organizers
Last document update:
ago
N5315 Advanced Pathophysiology

Hematologic System

Core Knowledge Objectives with Advanced Organizers

Disorders of Hemostasis

1. Examine the etiology, clinical manifestations, and the pathophysiology of disorders of

hemostasis.

a. Discuss how the
N5315 Advanced Pathophysiology

Endocrine

Prerequisite Knowledge Study Objectives

Hormones of the Hypothalamus and Pituitary Gland

1. Analyze the role of hormones produced by the hypothalamus and pituitary gland.

a. Create scripts for explaining the following to a patient or colleague in layman’s

terms which explain the glands of the endocrine system, the hormones they

produce, the target tissue and the hormone function to patients or colleag
N5315 Advanced Pathophysiology Endocrine Prerequisite Knowledge Study Objectives
Last document update:
ago
N5315 Advanced Pathophysiology

Endocrine

Prerequisite Knowledge Study Objectives

Hormones of the Hypothalamus and Pituitary Gland

1. Analyze the role of hormones produced by the hypothalamus and pituitary gland.

a. Create scripts for explaining the following to a patient or colleague in layman’s

terms which explain the glands of the endocrine system, the hormones they

produce, the target tissue and the hormone function to patients or colleag
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